Marini Thian
Associate Director, Toxicology Revolution Medicines
Dr. Marini Thian is an accomplished toxicologist specializing in nonclinical safety assessment for oncology and precision medicine therapeutics. At Revolution Medicines, she leads toxicology strategies for novel targeted therapies, guiding programs through IND-enabling studies and regulatory interactions. Her expertise spans multiple modalities including small molecules, biologics, ADCs, and cell & gene therapies across oncology, immunology, and rare diseases. Dr. Thian is recognized for her scientific rigor, strategic regulatory approach, and commitment to advancing innovative medicines through cross-functional collaboration and patient-focused safety assessment.
Seminars
Thursday 29th January 2026
Leveraging Predictive Models to Enhance Safety Testing in Oncology Development
1:45 pm
- Applying immune system predictive models to identify toxic responses early, providing confidence to accelerate development timelines
- Implementing novel in vitro approaches to generate preclinical data, offering robust evidence to reduce animal testing requirements
- Early detection of safety signals and weight-of-evidence approach to drive proactive risk mitigation strategy
