Deepali Sawant
Scientific Associate Director Amgen
Dr. Deepali Sawant is a Scientific Associate Director at Amgen, leading an in vivo pharmacology team supporting oncology pipeline programs. With 18+ years of research experience, she specializes in immunology, T cell biology, and cancer immunotherapy. Her team focuses on developing sophisticated preclinical models, including syngeneic systems with engineered stromal components and humanized models for evaluating T cell engagers, bispecific antibodies, and combination therapies. Dr. Sawant’s expertise spans target validation through translational biology, advancing novel immuno-oncology therapeutics from discovery to preclinical development.
Seminars
Wednesday 28th January 2026
Recapitulating Human Immune Components in Syngeneic Mouse Models to Maximize T Cell Engager Therapy Development
5:00 pm
- Overcoming the challenge of modeling human T cell responses in syngeneic mouse systems to enable accurate preclinical evaluation of T cell engager therapies
- Strategic approaches for recapitulating critical immune components within syngeneic models while maintaining physiological relevance for immunotherapy testing
- Translating preclinical insights from syngeneic models to inform clinical development strategies for T cell engager therapeutic candidates
