Translational Assessment of Safety Profile (Cytokine Release) of Therapeutics in Humanized Mouse Models

  • GenO-BRGSF-HIS recapitulate key CRS features induced by biologics tested in the clinic
  • Immune cells are recruited, polarized and activated into the tumor microenvironment in genO-BRGSF-HIS
  • GenO-BRGSF-HIS enables assessment of both efficacy and safety in a single model