Modeling Tumor Heterogeneity to Capture Variable Patient Responses in Oncology

• Evaluating inter-patient variability by leveraging diverse preclinical models to predict the range of clinical responses and identify potential non-responders
• Incorporating prior treatment history and resistance mechanisms in models to better reflect real-world patient populations and improve translational relevance
• Designing models that address intra-tumor heterogeneity to ensure reproducible and clinically meaningful preclinical efficacy data

Speakers:

Renumathy Dhanasekaran

Asst Prof

Stanford University